Anatomy of a Murder is about the murder trial of Lieutenant Manion. This courtroom crime drama boasts a sensational cast and these superb actors will most certainly keep you glued to your screen. James Stewart and George C. Scott lead the cast. Otto Preminger directed this film which was adapted by Wendell Mayes from the best-selling novel of the same name written by John D. Voelker whose pen name is Robert Traver. Voelker based his novel on a true-life murder case in which he was the defense attorney.